Symptom Burden Increases in Year Before Dialysis Initiation

TUESDAY, Nov. 15, 2022 (HealthDay News) — For older adults with kidney failure, symptom burden worsens in the year before initiation of dialysis and stabilizes thereafter, according to a study published online Nov. 10 in the Clinical Journal of the American Society of Nephrology.

Esther N.M. de Rooij, M.D., from the Leiden University Medical Center in the Netherlands, and colleagues examined the course of total and individual symptom number and burden before and after starting dialysis in patients aged 65 years and older from the European Quality study with an incident estimated glomerular filtration rate ≤20 mL/min/1.73 m². Thirty symptoms were assessed every six months between 2012 and 2021 using the dialysis symptom index (DSI). Data were included for 456 incident dialysis patients who completed at least one DSI in the year before or after dialysis.

The researchers found that symptom number increased +3.6 and symptom burden increased +13.3 in the year before dialysis initiation. In the year after, symptom number and burden decreased −0.9 and −5.9, respectively. The highest prevalence of symptoms was seen for “fatigue” (81 percent), “decreased interest in sex” (69 percent), and “difficulty becoming sexually aroused” (68 percent) at dialysis initiation, with burdens of 2.7, 2.4, and 2.3, respectively. After dialysis initiation, “fatigue” improved somewhat, while there was a further increase in the prevalence and burden of sexual symptoms.

“These results could help informing older patients with kidney failure who decided to start dialysis on what to expect regarding the development of their symptom burden,” the authors write.

Several authors disclosed financial ties to the pharmaceutical industry.

Abstract/Full Text

io io io io io io io io as as as as as as as as as as as as as as as as as as as as as as as as as as as as as as as as as as as as as as io io io io io io io io io as as as as as as as as io io io io io io io io io io io io io io as as as as as as as as as as as as as as as as as as as as as as as as as as as as as as as as as as as as as as io io io io io io io io as as as as as as as as as io io io io io io io io io io io io io io io as as as as as as as as as as as as as as as as as as as as as as as lisa171 lisa172 lisa173 lisa174 lisa175 lisa176 lisa177 lisa178 lisa179 lisa180 lisa181 lisa182 lisa183 lisa184 lisa185 lisa186 lisa187 lisa188 lisa189 lisa190 lisa191 lisa192 lisa193 lisa194 lisa195 lisa196 lisa197 lisa198 lisa199 lisa200 lisa201 lisa202 lisa203 lisa204 lisa205 lisa206 lisa207 lisa208 lisa209 lisa210

NewToNews

Symptom Burden Increases in Year Before Dialysis Initiation

Byolaksjl

By olaksjl

Related Post

Identifying the Phenotype of Frequent Acute Exacerbations in COPD Patients Based on Clinical & Imaging Characteristics

Pediatrician Career: The Intersection of Race/Ethnicity and Educational Debt

Banning Noncompete Contracts for Medical Staff Riles Hospitals

Leave a Reply Cancel reply

You missed

Researchers delve into the mechanisms of hereditary spastic paraplegia

Cerebral blood flow device; road traffic linked to hypertension

As Colorado reels from another school shooting, study finds 1 in 4 teens have quick access to guns

Study adds valuable new information on the treatment of COVID-19

NewToNews